OC-0241: MR radiomics predicting complete response in radiochemotherapy (RTCT) of rectal cancer (LARC)

Magnetic resonance tumor regression grade (MR-TRG) to assess pathological complete response following neoadjuvant radiochemotherapy in locally advanced rectal cancer

This study aims to evaluate the feasibility of a magnetic resonance (MR) automatic method for quantitative assessment of the percentage of fibrosis developed within locally advanced rectal cancers (LARC) after neoadjuvant radiochemotherapy (RCT). A total of 65 patients were enrolled in the study and MR studies were performed on 3.0 Tesla scanner; patients were followed-up for 30 months. The per...

Adjuvant radiochemotherapy for rectal cancer.

One of the basic questions for radiation oncologists is what we hope to achieve from treatments that are adjuvant to surgery. Can we achieve a better local control? Is there a decrease in metastatic disease? Can we see an effect on overall survival? Although some questions remain to be answered, some general recommendations for the treatment of rectal cancer can be given. Since the NIH recommen...

Comparison of 5FU-base Chemoradiation with and without Eloxatin on Pathologic Complete Response in Neoadjuvant Chemoradiation of Rectal cancer

  Background and Objectives: To compare pathologic complete response (pCR) in patients with advanced rectal cancer receiving neoadjuvant chemoradiotherapy (NACT) by 5-FU or Xeloda (capecitabine) with and without Eloxatin (oxaloplatin injection). Materials and Methods: Seventy-five consecutive patients with the diagnosis of advanced rectal adenocarcinoma were included. Two basic chemotherapy r...

Prostate cancer Radiomics using multiparametric MR imaging

Neoadjuvant radiotherapy and radiochemotherapy for rectal cancer.

Combined radiochemotherapy is the recommended standard postoperative therapy for patients with stage II and III rectal cancer in the USA and in Germany. During thelast decade, substantial progress has been made in treatment modalities: surgical management currently includes a broad spectrum of operative procedures ranging from radical operations such as abdominoperineal resections to innovative...